The National Institute for Health Research (NIHR), Clinical Research Network | 2012 | Source: The Guardian Volunteers involved with clinical trials are not human guinea pigs, but patients taking an active role in their healthcare, aiming to improve the quality of life for others with health conditions. John Whipps was… Continue reading
Ludman, E. J., Fullerton, S. M., Spangler, L., Trinidad, S. B., Fujii, M. M., Jarvik, G. P.,Burke, W. | Journal of Empirical Research on Human Research Ethics | September 2010 | NIH Public Access No consensus exists about when researchers need additional participant consent (re-consent) to submit existing data to… Continue reading
Singer, E., & Couper, M. P. | Journal of Empirical Research on Human Research Ethics | September 2010 | NIH Public Access For several years, we have experimented with various ways of communicating disclosure risk and harm to respondents in order to determine how these affect their willingness to participate… Continue reading
Bhansali S., Shafiq N., Malhotra S., Pandhi P., Singh I., Venkateshan S. P., Siddhu S., Sharma Y. P., Talwar K. K. | Contemporary Clinical Trials | 2009 | NCBI-PubMed | Abstract The comprehension of informed consent is an integral part of clinical trials. Though India is rapidly becoming a hub… Continue reading
David Wendler, Christine Grady | Bioethics | Vol. 22, Issue 4 | 31 July 2008 To give valid informed consent to participate in clinical research, potential participants should understand the risks, potential benefits, procedures, and alternatives. Potential participants also should understand that they are being invited to participate in research.… Continue reading
Ben Campbell | 2008 | Source: Dartmouth Ethics Institute | In the last decade, biomedical research conducted by researchers from developed countries in developing countries has been a topic of significant controversy. One serious concern is that research participants in the developing world are unable to give valid informed consent… Continue reading
Franklin G. Miller, Ezekiel J. Emanuel | The New England Journal of Medicine | 21 Feb 2008 Tens of thousands of patients die each year because of hospitals’ failure to adhere consistently to standard procedures of safe and effective medical care. Accordingly, improving the quality of routine hospital care is a… Continue reading
Hill Z., Tawiah-Agyemang C., Odei-Danso S., Kirkwood B. | Journal of Medical Ethics | 2008 | NCBI-PubMed ABSTRACT OBJECTIVES: To explore how subjects in a placebo-controlled vitamin A supplementation trial among Ghanaian women aged 15-45 years perceive the trial and whether they know that not all trial capsules are the… Continue reading
Flory, J., & Emanuel, E. | JAMA | 6 October 2004 | Vol. 292, No. 13 | Aim of article: To review research on interventions to improve research participants understanding of information disclosed in the informed consent process Read original article Also refer to:The Travesty of Informed Consent: Case of… Continue reading
Brown R. F., Butow P. N., Ellis P., Boyle F., Tattersall M. H. | Social Science and Medicine | June 2004 | NCBI-PubMed Abstract Clinical trials have come to be regarded as the gold standard for treatment evaluation. However, many doctors and their patients experience difficulties when discussing trials, leading… Continue reading
Eamnuel E. J., Wendler D., Killen J., Grady C. | The Journal of Infectious Diseases | Vol. 189, Issue 5 | Oxford Journals | 1 March 2004 In recent years, there has been substantial debate about the ethics of research in developing countries [1–5]. In general, the controversies have centered… Continue reading
Martin Tattersall | Cancer | American Cancer Society | Volume 95, Issue 7, pages 1397–1400 | 1 October 2002 Clinical trials are an essential component of modern health care. The results of randomized clinical trials increasingly define current standards of care. Potential new interventions, increasingly arising from basic research, require rigorous… Continue reading
